Complementary chemoenzymatic routes to both enantiomers of febrifugine.
نویسندگان
چکیده
Two complementary strategies for the synthesis of febrifugine are detailed based on previously developed chemoenzymatic approaches to the 3-hydroxypiperidine skeleton. The introduction of the quinazolone-containing side chain in both strategies was based on an N-acyliminium ion-mediated coupling reaction.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 7 14 شماره
صفحات -
تاریخ انتشار 2009